Complete Monster/Dreamworks Animation

Same as Disney, Dreamworks Animation has given us a number of despicable villains.

Dreamworks Films

 * General Mandible from Antz is a ruthless ant soldier that tried to drown his colony Queen and hoards of her loyal subjects in his attempts at seizing power for himself. What makes this truly terrible is when we learn about the reason why he planned to eradicate his own colony. His goal is not so much "ambition" as it is "purification"; he considers the worker ants weak-willed, undisiplined and uncomitted vermin, so he plans to build a new colony filled with (what he views as) the ideal ant. Does he reminds you someone by any chance...?
 * Going a bit further, when he told Cutter that a termite colony, one that was at peace with the ants for years, supposedly mobilized against their ant colony, Mandible immediately recommends sending troops, loyal to the queen, to attack the termite colony head-on; Cutter called it suicide, Mandible replied with "Exactly". Furthermore, Mandible seemed quite irritated when it turned out that there was one surviving soldier from the battle. When the Queen considered sending in an ambassador to renegotiate another treaty, Mandible claimed that "Every ant in this colony is precious to me", reminding her that they needed to attack while they still had the element of surprise, otherwise they'd face genocide by termite shock troops. When this persuaded the Queen to reluctantly approve of sending soldiers to attack, Mandible ominously replies with "You've ensured the future of this colony". Based on that whole exchange, it's implied that Mandible intended to kill off every part of the ant army that wasn't loyal to him in a suicide run, and may have even lied about the termites mobilizing against the ants at all.
 * Tzekel-Kan in The Road to El Dorado is the bloodthirsty high priest of El Dorado's religion. He specializes in Human Sacrifice, and when Miguel and Tulio arrive to his city, he believes that they are gods and tries to impress them by attempting to sacrifice an innocent citizen. Later, he comes out with the plan to "purify" the city of the unbelievers. He organizes the game between Miguel and Tulio, against a few citizens of El Dorado. When the citizens lose the game, Tzekel-Kan wants to sacrifice them before finding out that Miguel and Tulio are not gods. After that, Kan brings a statue of the Jaguar to life—in the process sacrificing his loyal servant—that destroys half the city. When this fails to kill Tulio and Miguel, Tzekel-Kan attempts to set a genocidal Hernán Cortés on his own people. Fanatical and sadistic, Tzekel-Kan embodies every stereotype Europeans had about the indigenous peoples.
 * How to Train Your Dragon mainstream franchise
 * Drago Bludvist of How to Train Your Dragon 2 is an unfeeling madman who seeks to take over Berk. Having lost his village and family to dragons when he was young, Drago subverts a Freudian Excuse by becoming exactly like the ones on whom he sought revenge against and using fear to dominate anyone in his path. Prior to the plot, Drago came to a chieftain's meeting and offered to drive away the dragons if they would kneel to him. When they declined, Drago responded by burning them alive and leaving no survivors but Stoick, Hiccup's father. In the plot, Drago raises a dragon army, led by a Bewilderbeast he abused into loyalty, and attempts to execute his right hand man for failing him, as well as the other dragon riders he brought with him. Drago enslaves the dragons living under Valka's care and kills their Alpha to assert his power. He even hypnotizes loyal Toothless to fire on his master, Hiccup, and simply scoffs when Stoick takes the blast instead. He then proceeds to lay waste to Berk with his new-found army, wishing to take no prisoners. Power hungry beyond salvation, Drago ended up putting even the first movie's Big Bad to shame.
 * Grimmel the Grisly is the Big Bad of How to Train Your Dragon: The Hidden World, who rivals the above-mentioned Drago Bludvist in darkness and depravity, the difference being in that while Drago was Stupid Evil, Grimmel is dangerously pragmatic. Having been hailed as a hero upon killing the first Night Fury he came across as a boy, Grimmel has hunted all but one to near extinction. Grimmel takes it upon himself to wipe out all dragons out of nothing more than Fantastic Racism and his own sadistic pleasure. In the present, Grimmel realizes Hiccup's dragon Toothless is the last Night Fury alive, so he invades Berk with an ultimatum of threatening to destroy everything Hiccup loves, before proceeding to torch his house and a whole part of Berk to the ground. Grimmel feels no empathy towards any living human or dragon, as evidenced by the treatment his six Deathgripper dragon slaves, who are drugged with mind controlling venom collars, and fed innocent baby Dragons to make them even more deadly. Upon the Dragon Riders' failed attempt to capture Grimmel, he traps them in his base and tries to burn them all alive with his Deathgrippers' flaming acid breath. In the climax, Grimmel succeeds in capturing Toothless and the Light Fury, threatening the latter's life to force Toothless to call the dragons to the warlords who hired him. He then prepares to butcher them all while betraying his warlord allies at the same time. Once foiled by Hiccup and the Dragon Riders, Grimmel enslaves the Light Fury with a venom collar, using her as his personal steed, and tries to drag Hiccup down with him upon being defeated for the final time. Ruthless, sadistic, and with no qualms as to who he must kill or hurt in pursuit of his own self gain, Grimmel proved to be an exceptionally dark villain in a film more lighthearted than its predecessors.

Dreamworks TV Series

 * Kung Fu Panda
 * Kung Fu Panda: Legends of Awesomeness has those two:
 * Tong Fo. While nearly all the villains of the franchise have at least one sympathetic or redeeming trait, the character most likely to be called a Complete Monster is Tong Fo, being Faux Affably Evil and seriously cruel and deranged. He makes his debut trying to destroy the Valley of Peace with a powerful hammer, seemingly for no reason other than because he can, as he never gives any reason for wanting to destroy the Valley. In "Father Crimes" when he manages to capture Shifu, he heavily implies that he's going to torture him, physically and mentally. In "Kung Fu Club", he blackmails Peng into fighting Po to the death by threatening to order Peng's girlfriend to be killed if he doesn't cooperate. On top are his repeated attempts to kill Po in nasty ways, in particular in "Mind Over Manners", where he pretends to want to help Po, then almost immediately reveals that the "help" in question will kill Po by making his head explode. And his reasoning for his life of crime is that he wants to live up to the legacy of his felon grandfather - by going even further than he ever could! His Christopher Walken impression voice can't even disguise what a total psychopath he is.
 * Ke-Pa, from "Enter the Dragon", is an ancient demon who terrorized the Valley of Peace with his army of demons, driving out or killing the citizens. After his army was sealed away by Oogway, Ke-Pa spent decades waiting for the peach tree that his powers are bound by dies, then, with his power returned, transformed into a dragon and lay siege to the Valley of Peace, threatening to eat the citizens one by one. Capturing and torturing Shifu under the belief that he has the Hero's Chi, Ke-Pa tries to crush the Hero's Chi out of him to free his demon army, before doing the same to Po and succeeding. Once his demons are unleashed, Ke-Pa orders them to kill everything in the Valley of Peace, bragging that he will destroy all mortals on the planet and reign supreme.
 * Kung Fu Panda: The Paws of Destiny: The Voice in the Shadows, aka Baigujing, aka the White Bone Demon, once roamed the land devouring souls of entire villages and leaving dolls behind to mark her crimes. When sealed away by Sun Wukong, the White Bone Demon eventually contacts Shi Long, corrupting the young girl into being her slave and using her to assassinate the Emperor, Shi Long's own adoptive father. Having Shi Long steal the Wellspring for her, the White Bone Demon's plans lead to a drought plaguing China, and Shi Long destroys entire villages to serve the White Bone Demon. The White Bone Demon's spirit inhabits a Humongous Mecha with Shi Long's help in the finale, betraying Shi Long and eating her alive before viciously trying to kill Po, his students the Four Constellations, and all of their friends before bringing an age of darkness onto China.
 * Dinotrux: D-Stroy (though only appearing in the second and final show in the series, Dinotrux: Supercharged) is the older, meaner brother of D-Structs, and a Chessmaster who outwits his opponents in almost any way. He first appears when he sees D-Structs cornered by many Scraptors, and pressures him to joining his cause, and later stalks him to see how his brother is trying to stop Ty and his friends. After that, he shows D-Structs the mother Dreadtrux the latter encountered much earlier, and ruthlessly abuses her into obedience, even telling her that she won't get any ore unless he says so. After he and D-Structs make a fake defeat, Ty and the gang unknowingly make new builds out of helium ore, which is what the Dreadtrux eats. When that happens, the D-Brothers and the Dreadtrux arrive and destroy all of the builds (and D-Stroy even comes dangerously close to gouging out Ty's eye with the grinders on his tail). With that, Ty and the gang are forced to leave, with D-Stroy assuring D-Structs that "the Crater is just the beginning". He gets even worse in Season 3 where he and D-Structs condemn the entire Crater to mass starvation, just to force them to turn against the hero. Eventually, after losing the Dreadtrux, the D-Brothers kick everyone out of the Crater, and on the brink of his final defeat, he betrays D-Structs by claiming he's weak. Cold, cruel, and calculating, D-Stroy is a surprisingly dark villain for the series he's in.
 * Voltron: Legendary Defender: Commander Sendak, ever a ruthless Galra commander, truly came into his own after the death of his sovereign Zarkon. After Prince Lotor takes the throne, Sendak becomes the leader of his own splinter faction, the Fire of Purification. He leads an attack on a Galra shield base to expose an entire colony to lethal radiation out of pure spite for being passed over for the throne. Later locating Earth, Sendak kills the soldiers sent against him and begins bombing and razing cities until the world surrenders to him, whereupon the citizens are enslaved and forced into work camps to create new weapons. Obsessed with finding Voltron and punishing the Lions' Paladins, Sendak makes a deal to spare Earth in exchange for the Lions, only to double back on it, and forcing the Paladins and the treacherous Admiral Sanda to watch as he intends to exterminate Earth and the billions who live there. When Voltron finally arrives to oppose him, Sendak ruthlessly kills entire ships full of his own men to get at the Paladins, and refuses to let any of his own crew get to safety, consumed with his own ambition and spite and taking the worst excesses of Galra to their natural conclusion. As cruel or ruthless as Emperor Zarkon, High Priestess Haggar and/or Crown Prince Lotor could be, they still can once in a while evoke the viewers' sympathies due to either their Tragic Mistakes or their Dark and Troubled Pasts; Sendak can not.
 * Tales of Arcadia
 * Trollhunters: Queen Usurna is the tyrannical Queen of the Krubera race. Centuries ago, she was responsible for trading Aarghaumont (more commonly known as "AAARRRGGHH!!!") and other younglings from her own race to Gunmar out of her fanaticism to him, selecting Aarghaumont to become his champion, thus causing Gunmar to raid his village and kidnap him from his family. After Gunmar was trapped in the Darklands, Usurna manipulates the Troll Tribunal by using their fear of Gunmar against them, causing them to indirectly keep Jim Lake, Jr. trapped in the Darklands because the Killahead Bridge was open, an action that would lead to a chain of events causing Gunmar's inevitable freedom. However, it's shown that she doesn't even care about Gunmar himself, as she was willing to leave him trapped in the Darklands forever when she claimed that Jim signed the death penalty when he entered it, making the decision that the Killahead Bridge should be dumped into the ocean where it can never be found again. To keep her tracks, she heartlessly murders Vendel, the Elder of Trollmarket, and frames it on Jim before leading Gunmar to Trollmarket to enslave all the innocent trolls there to become more Gumm-Gumms, even her own bodyguards. Following this, she has her bodyguards torture Aarghaumont by brutalizing him to teach him a lesson before attempting to drown him in thin mud.
 * 3Below: General Morando, the Big Bad of the second installment, was originally a military leader whose job was to protect his home planet, Akiridion-5, and his own species, the Akiridions, but he became power-hungry to the point where he tried to usurp the throne from King Fialkov and Queen Coranda. After being banished from Akiridion-5 for high treason even though the punishment for it was death, he engineered the bombing of Satellite Nine using the Zeron Brotherhood, which included Varvatos Vex's own family and hundreds of other civilians, to turn him into a traitor against his own species. Knowing that the King refused to pursue the Zerons and instead increased the planet's defenses, he manipulated him into betraying the King and Queen by lowering the shields, promising no one would be hurt. After that, he deliberately brakes his promise when he launches a full-scale attack on Akiridion-5 and easily takes over. He even launches a law that the Akiridions should worship him instead of praying for the Royals, with only one warning (plus, a child was among them), and sends his first OMEN to kill the Royals, with the entire planet being Forced to Watch. After this fails, he creates far more OMENs to terrorize his people, and even creates an asteroid the size of Arcadia to destroy Arcadia as a diversion to distract the Royals from him. He soon kills Tronos Madu (one of his bounty hunters) just for failing him, and murders an innocent, playful alien pet named Buster just because he "never liked bugs". After absorbing Gaylen's Core for himself, Morando decides to destroy the entire universe and remake it in his own image as a god.
 * Wizards: Skrael and Bellroc are a terrifying duo of sadistic entities who formed the Arcane Order together with Nari, believing that humanity were undeserving of the world because of them disturbing the balance between themselves magical beings, even though the Arcane Order themselves were no better. After Morgana was killed by King Arthur in an intense battle, she was resurrected by Skrael, Bellroc, and Nari, to use her for their plans. Eventually, during the Battle of the Killahead Bridge, Bellroc becomes responsible for King Arthur's death, and resurrect him afterwards to turn him into the Green Knight. Although Nari saw the errors of her ways, Skrael and Bellroc remained evil and sought to find the Genesis Seals so that they can consume the world in darkness and then wipe it clean of existence. Their actions have paved way for other evildoers through Morgana, whose actions not only indirectly caused Gunmar to free her so they can bring about the Eternal Night so she can rule the world, but also Morando to find Gaylen's Core so he can remake the universe, making Skrael and Bellroc the Overarching Villains of the entire franchise.
 * In She-Ra and the Princesses of Power, Horde Prime, the true ruler of the Horde, is an ancient being who exists by stealing the bodies of his clones who he breeds to be mindlessly loyal drones, any hint of individuality or imperfection resulting in erasure. Having exterminated countless worlds in the name of order, Prime is only swayed from destroying Etheria by the realization he can use it as a weapon, sending his discarded "brother" Hordak to have his identity erased. Later brainwashing Catra, Horde Prime tries to force Catra's suicide before Adora when she resists, using those he controls as weapons against their loved ones. Seeking to activate the Heart, Prime launches attacks on Etheria with threats to destroy the world, ending by trying to have Hordak himself kill his beloved Entrapta when she tries to warn him of the consequences. Finally activating the Heart, Horde Prime gleefully attempts to annihilate the entire universe as the ultimate culmination of order and his twisted ego.